proto-oncogene

See also: protooncogene

English

Etymology

proto- +‎ oncogene

Noun

proto-oncogene (plural proto-oncogenes)

(genetics) A gene, that promotes the specialization and division of normal cells, that becomes an oncogene following mutation.
- 2010, Siddhartha Mukherjee, The Emperor of All Maladies, Fourth Estate (2011), page 534:
  Typically, proto-oncogenes are normal cellular genes that, when activated by mutation or overexpression, promote cancer.

References

Lodish, Harvey; Berk, Arnold; Zipursky, Lawrence S.; Matsudaira, Paul; Baltimore, David; Darnell, James (2000), “Glossary”, in Molecular Cell Biology‎ (in English), Fourth edition edition, New York, N.Y.: W. H. FREEMAN, →ISBN, retrieved 11 December 2009

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