Laurie Boyer

Laurie A. Boyer is an American biomedical engineer who is a professor at the Massachusetts Institute of Technology. Her research considers embryonic stem cells and cardiac development.

Laurie A. Boyer
Boyer in 2020.jpg
Alma materSaint Louis University
University of Massachusetts Chan Medical School
Framingham State University
Scientific career
InstitutionsMassachusetts Institute of Technology
ThesisConserved features of chromatin remodeling enzymes : a dissertation (2000)

Early life and education

Boyer is from western Massachusetts.[1] She became interested in science and biology whilst at high school.[1] She was an undergraduate student at Framingham State University where she studied biomedical sciences. She moved to the University of Massachusetts Chan Medical School, where she researched chromatin remodeling enzymes.[2][3] She earned a doctorate at Saint Louis University, where she investigated safety cultures in the aviation and healthcare sectors.[4] She worked as a postdoctoral research at the MIT Whitehead Institute.[1]

Research and career

Boyer investigates cardiac development, and how different genes affect heart development. In particular, she has investigated cardiomyocytes and how they repeatedly contract and relax. An overarching question of her research is how cardiomyocytes assemble into their apparatus for contacting.[5] She has studied heart development in people with Trisomy-21, half of whom have heart defects. The most common condition is an Atrioventricular septal defect. Boyer worked with Angelika Amon to identify the faulty signals in Trisomy-21 cardiac cells that can damage heart development.[5]

Awards and honors

Selected publications
  • Laurie A Boyer; Tong Ihn Lee; Megan F Cole; et al. (23 September 2005). "Core transcriptional regulatory circuitry in human embryonic stem cells". Cell. 122 (6): 947–56. doi:10.1016/J.CELL.2005.08.020. ISSN 0092-8674. PMC 3006442. PMID 16153702. Wikidata Q24322016.
  • Laurie A Boyer; Kathrin Plath; Julia Zeitlinger; et al. (19 April 2006). "Polycomb complexes repress developmental regulators in murine embryonic stem cells". Nature. 441 (7091): 349–353. doi:10.1038/NATURE04733. ISSN 1476-4687. PMID 16625203. Wikidata Q29547274.
  • Kundaje A; Meuleman W; Ernst J; et al. (19 February 2015). "Integrative analysis of 111 reference human epigenomes". Nature. 518 (7539): 317–30. doi:10.1038/NATURE14248. ISSN 1476-4687. PMC 4530010. PMID 25693563. Wikidata Q29615565.

References
  1. Sedwick, Caitlin (2012-10-15). "Laurie Boyer: Stem cell circuitry for commitment". Journal of Cell Biology. 199 (2): 190–191. doi:10.1083/jcb.1992pi. ISSN 0021-9525. PMC 3471231. PMID 23071147.
  2. Boyer, Laurie A (2000). Conserved features of chromatin remodeling enzymes: a dissertation (Thesis). OCLC 47147047.
  3. "Allen Discovery Center Opening Event at the Science & Engineering Complex". Allen Discovery Center at Tufts University. Retrieved 2022-05-25.
  4. Boyer, Laurie A (2005). Comparison of safety cultures between healthcare organizations and aviation organizations (Thesis). OCLC 137272785.
  5. "Queen of hearts". MIT News | Massachusetts Institute of Technology. Retrieved 2022-05-25.
  6. "Scientific American 50: SA 50 Winners and Contributors". Scientific American. Retrieved 2022-05-25.
  7. staff, John Hilliard/Daily News. "MIT professor to speak at FSC graduation". MetroWest Daily News. Retrieved 2022-05-25.
  8. "Laurie Boyer, Ph.D.—VARI Seminar Series". Van Andel Institute for Research. Retrieved 2022-05-30.
  9. "Smith Family Awards Program for Excellence in Biomedical Research". Health Resources in Action. Retrieved 2022-05-25.
  10. "Who's presenting at Research Week 2016? Announcing this year's keynotes | OHSU Research News". OHSU Research News | Research News at OHSU. 2016-03-24. Retrieved 2022-05-25.
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