Cardiotoxin III
Cardiotoxin III (CTX III, also known as cytotoxin 3) is a sixty amino-acid polypeptide toxin from the Taiwan Cobra Naja atra. It is an example of a group of snake cardio/cytotoxins (InterPro: IPR003572), which are made up of shorter snake venom three-finger toxins.[1]
| Cytotoxin 3 | |||||||
|---|---|---|---|---|---|---|---|
 | |||||||
| Identifiers | |||||||
| Organism | |||||||
| Symbol | ? | ||||||
| PDB | 1H0J | ||||||
| UniProt | P60301 | ||||||
| |||||||
Recent evidence has shown that CTX III may induce apoptosis in K562 cells via the release of cytochrome c.[2]
References
- "Superfamily » 2.2.39. Snake toxin-like (2 families) - Orientations of Proteins in Membranes (OPM) database". Retrieved 2008-12-13.
- Yang SH, Chien CM, Lu MC, Lu YJ, Wu ZZ, Lin SR (July 2005). "Cardiotoxin III induces apoptosis in K562 cells through a mitochondrial-mediated pathway". Clin. Exp. Pharmacol. Physiol. 32 (7): 515–20. doi:10.1111/j.1440-1681.2005.04223.x. PMID 16026508. S2CID 29082467.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.