Diclofenac/misoprostol
| Combination of | |
|---|---|
| Diclofenac | NSAID |
| Misoprostol | Prostaglandin analog |
| Clinical data | |
| Pregnancy category |
|
| Routes of use | By mouth |
| External links | |
| US NLM | Diclofenac/misoprostol |
| MedlinePlus | a699002 |
| Legal | |
| Legal status | |
| Identifiers | |
| CAS Number |
|
| KEGG | |
| ATC code | |
Diclofenac/misoprostol, sold under the brand name Arthrotec, is a fixed-dose combination medication that contains:
- Diclofenac sodium: Nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties
- Misoprostol: Gastrointestinal (GI) mucosal protective prostaglandin E1 analog.
In the United Kingdom it is available in two strengths. It is marketed by Pharmacia and its indication is for prophylaxis against NSAID-induced gastroduodenal ulceration in patients requiring diclofenac for rheumatoid arthritis or osteoarthritis.Arthrotec must not be taken during pregnancy, as it may deform or otherwise harm the fetus, or lead to miscarriage. This may be accompanied by potentially dangerous bleeding, possibly requiring surgery and potentially leading to infertility or death.[1]
Society and culture
Cost
This medication is in the U.S. available for $57 (USD) for an amount of 30 tablets (50 mg-200 mcg) [2]
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DiclofenacSodiumMisoprostol costs (US).svg.png.webp)
DiclofenacSodiumMisoprostol prescriptions (US)
References
External links
- "Diclofenac mixture with Misoprostol". Drug Information Portal. U.S. National Library of Medicine. Archived from the original on 2021-08-28. Retrieved 2020-09-25.
- Access to Summary of Product Characteristics for Diclofenac
- Summary of Product Characteristics Archived 2007-09-28 at the Wayback Machine for Arthrotec 50 from the electronic Medicines Compendium
- Patient Information Leaflet Archived 2007-09-28 at the Wayback Machine for Arthrotec 50 from the electronic Medicines Compendium
- Summary of Product Characteristics Archived 2007-09-28 at the Wayback Machine for Arthrotec 75 from the electronic Medicines Compendium
- Patient Information Leaflet Archived 2007-09-28 at the Wayback Machine for Arthrotec 75 from the electronic Medicines Compendium
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