hypercondensation

English

Etymology

hyper- +‎ condensation

Noun

hypercondensation (countable and uncountable, plural hypercondensations)

  1. (organic chemistry) A class of condensation reaction involving reaction of a carbonyl group with a methylene group to form an alkene with the loss of the elements of water (>C=O + CH2< -> >C=C<)
  2. (genetics) The severe compaction of chromosomes
    • 2015 October 23, “Structure-Activity Relationship of Synthetic 2-Phenylnaphthalenes with Hydroxyl Groups that Inhibit Proliferation and Induce Apoptosis of MCF-7 Cancer Cells”, in PLOS ONE‎, DOI:10.1371/journal.pone.0141184:
      In addition, PNAP - 6h decreased CDK1 and cyclin B1 expression, most likely leading to G 2 /M arrest, and induced morphological changes, such as nuclear shrinkage, nuclear fragmentation, and nuclear hypercondensation, as observed by Hoechst 33342 staining.
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