Mucin-1

Mucin-1 (MUC-1) is a transmembrane protein of the mucin family encoded in the human by the MUC1 gene.[1] [2]It is cleaved into two chains: Mucin-1 subunit alpha (MUC1-NT; MUC1-alpha) and Mucin-1 subunit beta (MUC1-beta) Alternative names: MUC1-CT

Mucin-1 is located only in the apical membrane of polarised epithelial cells. It is secreted by endocytosis, after which it is internalised and recycled to the cell membrane.

References

  1. "UniProt". www.uniprot.org. Retrieved 7 November 2022.
  2. "MUC1 Gene - GeneCards | MUC1 Protein | MUC1 Antibody". www.genecards.org. Retrieved 7 November 2022.


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